colona 40 tab
Reference Priceكولونا 40 قرص
mebeverine+sulpiridePublic price92EGP
The published official price. Pharmacies may differ slightly.
Save 74 EGP (80%) with an identical form equivalent
Cheaper equivalent sharing the exact same active ingredient & dosage form: spasmo amrase 20 e.c. tab (18 EGP)
Formtablet
Manufacturerrameda
Routeoral.solid
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
This combination is indicated for irritable bowel syndrome (IBS) and functional colonic disorders characterized by abdominal pain, spasm, bloating, and altered bowel habits with an associated anxiety or psychosomatic component.
Do not use if
Contraindicated in hypersensitivity to either component, pheochromocytoma, prolactin-dependent tumors, pregnancy, severe renal impairment, and in patients with Parkinson's disease or other conditions where dopamine antagonism is harmful.
Side effects
Mebeverine may cause rare allergic reactions including urticaria and angioedema. Sulpiride may cause extrapyramidal symptoms, hyperprolactinemia, sedation, and tardive dyskinesia with prolonged use.
Warnings
Sulpiride may lower the seizure threshold; use with caution in epileptic patients. May prolong the QT interval; avoid in patients with known QT prolongation. Long-term use carries risk of tardive dyskinesia.
How it works
Mebeverine is a direct-acting antispasmodic that relaxes intestinal smooth muscle without anticholinergic effects. Sulpiride is a selective dopamine D2 receptor antagonist with anxiolytic and antiemetic properties, addressing the psychosomatic component of IBS.
Storage
Store at room temperature (15–25°C), protected from moisture and light.